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KMID : 0381319770160020047
Korean Journal of Occupational Health
1977 Volume.16 No. 2 p.47 ~ p.58
Maximal Expiratory Flow-Volume Curve in Pneumoconiosis


Abstract
Maximal expiratory flow-volume (MEFV) curves were obtained in groups of 53 healthy subjects and 157 pneumoconiosis patients from coal mines, in order to study the ventilatory mechanics of pulmonary impairment according to grades of pneumoconiosis by x-ray findings and the types of ventilatory pattern and peak flow rate(PER), maximal expiratory flow rates at 25 percent, 50 percent and 75 percent of vital capacity, slop of the curve over the volume range of 25 to 50 percent of vital capacity(??/??_(25-50)) and ?_(50)/?_(25) ratio were measured.
1. In healthy subjects, mean values of PER, ?_(75), ?_(50),?_(25), ??/??(25-50) and ?_(50)/?_(25) ratio were 8.0§¤/sec, 6.9§¤/sec, 4.0§¤/sec, 1.7§¤/sec, 2.4§¤/sec/§¤ and 2.53 respectively, and PFR and maximal expiratory flow rates at various lung volumes were significantly lower in the older subjects(50-59 years) than in the younger.
2. ?_(25) and ?_(50)/?_(25) ratio may be useful index for the purpose of evaluating the effect of age on MEFV curve in healthy subjects.
3. Mean values of MEFV curve indices of the pneumoconiosis patients were significantly lower than those of normal subjects of the comparable age. Single index usful in assessing the presence and the severity of respiratory impairment in pneumoconiosis seems to be the maximal expiratory flow rate at 50 percent of vital capacity.
4. MEFV curve indices showed no significant association with the profusion and showed increasing tendency in inverse proportion with the size of small opacity in simple pneumoconiosis.
5. MEFV curve indices were more abnormal values in pneumoconiosis patients complicated with pulmonary tuberculosis than in simple pneumoconiosis patients.
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